MEDICAL MILESTONES
A chronology of the key events in medical history that changed our view of death
400s - 300s B.C.
Hippocrates lives; clinical study of disease, anatomy and surgery begins; earliest medical schools founded.

1600s - 1700s A.D.
Modern anatomy begins; microscope comes into medical use; great strides made in chemistry and pharmacy; high mortality remains for amputations and childbirth; half of all amputations end in death.

Late 1700s
Medical diagnoses continue to be oversimplified as "fever" or "inflammation;" supernatural causes such as divine retribution for sins frequently blamed for diseases and death.

Early 1800s
Vaccinations for smallpox and other diseases broadly available; stethoscope invented; life expectancy at birth less than 40 years.

Late 1800s
Bacteriology debuts; some hospitals open labs to study blood, gastric contents, tissue samples, bodily fluids; infections no longer blamed on "bad air;" surgery survival rates improve dramatically.

Mid-1900s
Immunology and virology flourish; life expectancy at birth in United States rises to about 65 for men and 70 for women.

Post-World War II
Life-extending breakthroughs unfold; penicillin proves practical, ushers in era of antibiotics; ventilators gain widespread use in hospitals; polio vaccine developed; RNA, DNA synthesized; first artificial heart replaces a human heart in surgery; organ transplants successful; great strides made in research and treatment of cancer, diabetes, arthritis; human life expectancy rises as a global dialog emphasizes quality of life as well as length; in 1946, the World Health Organization adopts this statement in the preamble to its Constitution, "Health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity."

Late 1990s
Life expectancy at birth in United States is 73 for men and 80 for women; U.S. infant mortality rate drops to 76 deaths per 10,000 live births, down from 260 in 1960.

Data researched and compiled by Jenny Strasburg and Jef Dauber, Scripps Howard News Service.

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